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  • ASTM
    D6259-15 Standard Practice for Determination of a Pooled Limit of Quantitation for a Test Method
    Edition: 2015
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Description of ASTM-D6259 2015

ASTM D6259-15

Historical Standard: Standard Practice for Determination of a Pooled Limit of Quantitation for a Test Method




ASTM D6259

Scope

1.1 This practice covers the use of standard regression techniques and data from an interlaboratory study to determine a lower quantitative limit for a test method. This determined lower limit represents the numerical limit at or above which the test results are considered to be quantitatively meaningful for commerce or regulatory activities by this practice. It is defined by this standard as the pooled limit of quantitation (PLOQ) for the test method.

1.2 This practice is applicable to test methods that are capable of producing numerical test results close to zero. Examples are those test methods that determine quantitatively the concentration of analyte(s) near zero.


Keywords

limit of quantitation; pooled limit of quantitation;


ICS Code

ICS Number Code 19.020 (Test conditions and procedures in general)


DOI: 10.1520/D6259-15

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About ASTM

ASTM International, formerly known as the American Society for Testing and Materials (ASTM), is a globally recognized leader in the development and delivery of international voluntary consensus standards. Today, some 12,000 ASTM standards are used around the world to improve product quality, enhance safety, facilitate market access and trade, and build consumer confidence. ASTM’s leadership in international standards development is driven by the contributions of its members: more than 30,000 of the world’s top technical experts and business professionals representing 150 countries. Working in an open and transparent process and using ASTM’s advanced electronic infrastructure, ASTM members deliver the test methods, specifications, guides, and practices that support industries and governments worldwide.
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