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  • ASTM
    F2664-07 Standard Guide for Assessing the Attachment of Cells to Biomaterial Surfaces by Physical Methods
    Edition: 2007
    $93.60
    Unlimited Users per year

Description of ASTM-F2664 2007

ASTM F2664-07

Historical Standard: ASTM F2664-07 Standard Guide for Assessing the Attachment of Cells to Biomaterial Surfaces by Physical Methods

SUPERSEDED (see Active link, below)




ASTM F2664

1. Scope

1.1 This guide describes protocols that can be used to measure the strength of the adhesive bond that develops between a cell and a surface as well as the force required to detach cells that have adhered to a substrate. Controlling the interactions of mammalian cells with surfaces is fundamental to the development of safe and effective medical products. This guide does not cover methods for characterizing surfaces. The information generated by these methods can be used to obtain quantitative measures of the susceptibility of surfaces to cell attachment as well as measures of the adhesion of cells to a surface. This guide also highlights the importance of cell culture history and influences of cell type.

This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.


2. Referenced Documents (purchase separately) The documents listed below are referenced within the subject standard but are not provided as part of the standard.

ASTM Standards

D4410 Terminology for Fluvial Sediment

F22 Test Method for Hydrophobic Surface Films by the Water-Break Test

F2312 Terminology Relating to Tissue Engineered Medical Products

F2603 Guide for Interpreting Images of Polymeric Tissue Scaffolds

ISO Standards

ISO 13565-1 Geometrical Product Specifications (GPS)--Surface Texture: Profile Method; Surfaces Having Stratified Functional Properties--Part 1: Filtering and General Measurement Conditions

ICS Code

ICS Number Code 07.080 (Biology. Botany. Zoology); 07.100.01 (Microbiology in general)


DOI: 10.1520/F2664-07

ASTM International is a member of CrossRef.


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About ASTM

ASTM International, formerly known as the American Society for Testing and Materials (ASTM), is a globally recognized leader in the development and delivery of international voluntary consensus standards. Today, some 12,000 ASTM standards are used around the world to improve product quality, enhance safety, facilitate market access and trade, and build consumer confidence. ASTM’s leadership in international standards development is driven by the contributions of its members: more than 30,000 of the world’s top technical experts and business professionals representing 150 countries. Working in an open and transparent process and using ASTM’s advanced electronic infrastructure, ASTM members deliver the test methods, specifications, guides, and practices that support industries and governments worldwide.

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